STAT3 Products
The STAT family of transcription factors, first described as key mediators of interferon signal transduction, are now recognized as signaling factors downstream of many cytokines, growth factors, and hormones. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. They are characterized structurally by the presence of the Src homology 2 (SH2) domain, and a C-terminal tyrosine phosphorylation site. Upon ligand binding, they are recruited to the activated receptor, via their SH2 domains, to receptor-associated tyrosine kinases of the Janus kinase family (JAK). Once phosphorylated by JAK, STATS are free to hetero- or homo-dimerize, and translocate to the nucleus where they bind DNA to regulate gene transcription.
367 results for "STAT3" in Products
367 results for "STAT3" in Products
STAT3 Products
The STAT family of transcription factors, first described as key mediators of interferon signal transduction, are now recognized as signaling factors downstream of many cytokines, growth factors, and hormones. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. They are characterized structurally by the presence of the Src homology 2 (SH2) domain, and a C-terminal tyrosine phosphorylation site. Upon ligand binding, they are recruited to the activated receptor, via their SH2 domains, to receptor-associated tyrosine kinases of the Janus kinase family (JAK). Once phosphorylated by JAK, STATS are free to hetero- or homo-dimerize, and translocate to the nucleus where they bind DNA to regulate gene transcription.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #232209 |
| Applications: | WB, IP, ICC, ICFlow, KO |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #788335 |
| Applications: | WB, ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, ELISA, ICC/IF, Flow |
![Immunocytochemistry/ Immunofluorescence: STAT3 Antibody [NB100-799]](https://resources.bio-techne.com/images/products/STAT3-Antibody-Immunocytochemistry-Immunofluorescence-NB100-799-img0005.jpg "Immunocytochemistry/ Immunofluorescence: STAT3 Antibody [NB100-799]")
| Reactivity: | Human, Mouse, Rat, Canine, Primate, +1 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: STAT3 [p Tyr705] Antibody [NBP2-24463]](https://resources.bio-techne.com/images/products/STAT3-[p-Tyr705]-Antibody-Western-Blot-NBP2-24463-img0003.jpg "Western Blot: STAT3 [p Tyr705] Antibody [NBP2-24463]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SY24-09 |
| Applications: | IHC, WB, ICC/IF, IP |
| Assay Range: | 2344 - 150,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #RM261 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Rat IgG2b Monoclonal Clone #805435 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, Simple Western |
![Western Blot: STAT3 [p Tyr705] Antibody [NB100-82213]](https://resources.bio-techne.com/images/products/STAT3-[p-Tyr705]-Antibody-Western-Blot-NB100-82213-img0001.jpg "Western Blot: STAT3 [p Tyr705] Antibody [NB100-82213]")
| Reactivity: | Human, Mouse, Rat, Zebrafish |
| Details: | Rabbit IgG Monoclonal Clone #SY24-08 |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: STAT3 Antibody (SY24-08) [NBP2-67432]](https://resources.bio-techne.com/images/products/STAT3-Antibody-SY24-08-Western-Blot-NBP2-67432-img0009.jpg "Western Blot: STAT3 Antibody (SY24-08) [NBP2-67432]")
| Reactivity: | Human |
| Details: | Rabbit IgG2b Monoclonal Clone #1004G |
| Applications: | WB, Simple Western, ICFlow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #232209 |
| Applications: | ICFlow, KO |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ChIP |
![Western Blot: STAT3 Antibody [NBP2-38857]](https://resources.bio-techne.com/images/products/STAT3-Antibody-Western-Blot-NBP2-38857-img0006.jpg "Western Blot: STAT3 Antibody [NBP2-38857]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0492 |
| Applications: | IHC, WB, ICC/IF, Mycoplasma |
![Western Blot: STAT3 Antibody (CL0492) [NBP2-52936]](https://resources.bio-techne.com/images/products/STAT3-Antibody-CL0492-Western-Blot-NBP2-52936-img0006.jpg "Western Blot: STAT3 Antibody (CL0492) [NBP2-52936]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI21E7 |
| Applications: | IHC, WB, KO |
![Knockout Validated: STAT3 Antibody (OTI21E7) [NBP1-48014]](https://resources.bio-techne.com/images/products/STAT3-Antibody-OTI21E7-Western-Blot-NBP1-48014-img0013.jpg "Western Blot: STAT3 Antibody (OTI21E7) [NBP1-48014]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI21E7 |
| Applications: | IHC, WB, KO |
![Western Blot: STAT3 Antibody (OTI21E7)Azide and BSA Free [NBP2-74378]](https://resources.bio-techne.com/images/products/STAT3-Antibody-OTI21E7-Azide-and-BSA-Free-Western-Blot-NBP2-74378-img0003.jpg "Western Blot: STAT3 Antibody (OTI21E7)Azide and BSA Free [NBP2-74378]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: STAT3 AntibodyBSA Free [NBP2-41208]](https://resources.bio-techne.com/images/products/STAT3-Antibody-Western-Blot-NBP2-41208-img0001.jpg "Western Blot: STAT3 AntibodyBSA Free [NBP2-41208]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #232209 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0492 |
| Applications: | IHC, WB, ICC/IF |
![STAT3 Antibody (CL0492) - Azide and BSA Free Immunocytochemistry/ Immunofluorescence: STAT3 Antibody [NBP3-43941]](https://resources.bio-techne.com/images/products/nbp3-43941_mouse-stat3-mab-cl0492-azide-and-bsa-free-2822025129110.jpg "Immunocytochemistry/ Immunofluorescence: STAT3 Antibody [NBP3-43941]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #788335 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0490 |
| Applications: | IHC, WB, Mycoplasma |
![Western Blot: STAT3 Antibody (CL0490) [NBP2-52935]](https://resources.bio-techne.com/images/products/STAT3-Antibody-CL0490-Western-Blot-NBP2-52935-img0005.jpg "Western Blot: STAT3 Antibody (CL0490) [NBP2-52935]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #232209 |
| Applications: | ICFlow |