Somatostatin R2/SSTR2: Small Molecules and Peptides
Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both SSTR2 isoforma are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.
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4 results for "Somatostatin R2/SSTR2 Small Molecules and Peptides" in Products
Somatostatin R2/SSTR2: Small Molecules and Peptides
Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both SSTR2 isoforma are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.
Endogenous neuropeptide; binds sst1 - sst5, ghrelin receptor and MRGPRX2
| Alternate Names: | CST-14 |
| Purity: | ≥95% (HPLC) |
Selective sst2 antagonist
| Purity: | ≥95% (HPLC) |
Non-selective sst antagonist
| Alternate Names: | Cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[BZL]) |
| Purity: | ≥95% (HPLC) |
sst2, sst3 and sst5 agonist
| Alternate Names: | SMS 201995,Sandostatin |
| Purity: | ≥95% (HPLC) |