Octreotide
Tocris Bioscience, part of Bio-Techne | Catalog # 1818
sst2, sst3 and sst5 agonist
Key Product Details
Description
sst2, sst3 and sst5 agonist
Alternative Names
SMS 201995,Sandostatin
Product Description
Octreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 - 1140 (sst1), 0.4 - 2.1 (sst2), 4.4 - 34.5 (sst3), > 1000 (sst4), and 5.6 - 32 (sst5).Product Specifications
Molecular Weight
1019.24
Formula
C49H66N10O10S2
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
83150-76-9
PubChem ID
90488715
InChI Key
DEQANNDTNATYII-XOEBDJBESA-N
SMILES
[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)O)C(=O)N[C@H](CO)[C@@H](C)O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1.2mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Raynor Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding to linear peptides. Mol.Pharmacol. 1993 PMID: 8100350
- Hannon Drug design at peptide receptors. Somatostatin receptor ligands. J.Mol.Neurosci.
- Hoyer Molecular pharmacology of somatostatin receptors. Naunyn Schmiedebergs Arch.Pharmacol. 1994 PMID: 7870182
Product Specific Notices for Octreotide
For research use only
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