8 results for "SLC6A3/DAT1 Small Molecules and Peptides" in Products
SLC6A3/DAT1: Small Molecules and Peptides
The dopamine transporter (DAT) is a 70 - 80 kDa member of the Na+-neurotransmitter symporter family of transmembrane (TM) proteins. DAT plays a crucial role in the synaptic clearance of dopamine (DA). It mediates the uptake of dopamine by the presynaptic terminal, thus limiting the strength of the dopamingeric response. One molecule of DA is accompanied by two Na+ and one Cl- ion. Molecules such as amphetamine both competitively inhibit DA uptake, and induce DA release through the DAT, ...
5-HT reuptake inhibitor
| Chemical Name: | (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
| Chemical Name: | 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate |
| Purity: | ≥98% (HPLC) |
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake
| Chemical Name: | (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake
| Alternate Names: | Lu 19-005 |
| Chemical Name: | (1R,3S)-rel-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-amine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective DA uptake inhibitor
| Chemical Name: | 1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity dopamine uptake inhibitor
| Chemical Name: | (3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective inhibitor of dopamine and noradrenalin transporters
| Chemical Name: | 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective DA uptake inhibitor; also σ ligand
| Chemical Name: | 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride |
| Purity: | ≥98% (HPLC) |
