11 results for "SLC6A2/NET Small Molecules and Peptides" in Products
SLC6A2/NET: Small Molecules and Peptides
Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression (Klimek et al., 1997). Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD (Kim et al., 2006).
Endogenous adrenergic hormone and neurotransmitter
| Alternate Names: | Norepinephrine |
| Chemical Name: | 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol (L-(+))-bitartrate salt |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of noradrenalin transporters
| Chemical Name: | 10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent inhibitor of vesicular monoamine transport
| Chemical Name: | (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one |
| Purity: | ≥98% (HPLC) |
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
| Chemical Name: | 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate |
| Purity: | ≥98% (HPLC) |
Potent and selective noradrenalin re-uptake inhibitor
| Alternate Names: | Atomoxetine,LY 139603 |
| Chemical Name: | (R)-N-Methyl-γ-(2-methylphenoxy)-benzenepropanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Noradrenalin re-uptake inhibitor
| Chemical Name: | (±)-γ-(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective noradrenalin uptake inhibitor; orally active
| Chemical Name: | (2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate |
| Purity: | ≥98% (HPLC) |
5-HT and NA reuptake inhibitor (SNRI)
| Alternate Names: | Wy 45030 |
| Chemical Name: | 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective inhibitor of dopamine and noradrenalin transporters
| Chemical Name: | 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake
| Chemical Name: | (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake
| Alternate Names: | Lu 19-005 |
| Chemical Name: | (1R,3S)-rel-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-amine hydrochloride |
| Purity: | ≥98% (HPLC) |
