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205 results for "PRAS40" in Products

PRAS40 Products

PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #23GB645
Applications: WB, ICC/IF, Flow, Mycoplasma

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #JE30-60
Applications: IHC, WB, ICC/IF, Flow
PRAS40 Antibody (JE30-60)
(4)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: PRAS40 AntibodyBSA Free [NBP2-41221]
(3)
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