PRAS40 Products
PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.
171 results for "PRAS40" in Products
171 results for "PRAS40" in Products
PRAS40 Products
PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #760502 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, Simple Western, ICC |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1211A |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1211A |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE30-60 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #660928 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #760502 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #760502 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #760502 |
| Applications: | WB, ICC |