Leptin/OB Products
Leptin, also known as OB, is a polypeptide hormone that regulates adipose tissue mass and energy balance. In mice (ob/ob) and humans, inactivating mutations of the OB gene can cause obesity. Leptin signals through the transmembrane Leptin R in the hypothalamus but can also bind shorter and soluble forms of Leptin R which do not signal. Adipocytes increase Leptin expression as cell size increases, resulting in depressed appetite and increased energy expenditure. Low Leptin levels prompt increased appetite and decreased energy expenditure. Leptin can also block the onset of puberty or menses during starvation, extreme exercise-induced weight loss, anorexia, or cancer-induced cachexia.
337 results for "Leptin/OB" in Products
337 results for "Leptin/OB" in Products
Leptin/OB Products
Leptin, also known as OB, is a polypeptide hormone that regulates adipose tissue mass and energy balance. In mice (ob/ob) and humans, inactivating mutations of the OB gene can cause obesity. Leptin signals through the transmembrane Leptin R in the hypothalamus but can also bind shorter and soluble forms of Leptin R which do not signal. Adipocytes increase Leptin expression as cell size increases, resulting in depressed appetite and increased energy expenditure. Low Leptin levels prompt increased appetite and decreased energy expenditure. Leptin can also block the onset of puberty or menses during starvation, extreme exercise-induced weight loss, anorexia, or cancer-induced cachexia.
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #44802 |
| Applications: | Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #44804 |
| Sensitivity: | 5.56 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Tissue Homogenates, Mouse Serum, Rat Serum, Mouse EDTA Plasma, Rat EDTA Plasma, Mouse Heparin Plasma, Rat Heparin Plasma) |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2299B |
| Applications: | WB, ELISA, IHC |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2299A |
| Applications: | ELISA, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2299A |
| Applications: | ELISA, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2299B |
| Applications: | WB, ELISA, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human, Mouse, Rat, Porcine, Sheep, +1 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Leptin/OB Antibody [NB300-611]](https://resources.bio-techne.com/images/products/Leptin-OB-Antibody-Western-Blot-NB300-611-img0005.jpg "Western Blot: Leptin/OB Antibody [NB300-611]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #44802 |
| Applications: | ELISA(Cap), ELISA(Det), Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #44802 |
| Applications: | ELISA(Cap), ELISA(Det), Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #44802 |
| Applications: | ELISA(Cap), ELISA(Det), Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #44802 |
| Applications: | ELISA(Cap), ELISA(Det), Neut |