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270 results for "Lck" in Products

Lck Products

Lck (p56lck) is a member of the Src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and over-expressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene. Lck behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show over-expression of Lck, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers.

Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins

Reactivity:
Human
Detection of human protein kinase phosphorylation in A549 Cell Line.
(4)
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #755103
Applications:
WB, ICC/IF
Detection of Human Phospho-Lck (Y394) antibody by Western Blot.
(4)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, Simple Western
Detection of Human Lck antibody by Western Blot.
(4)

Potent, selective Src family kinase inhibitor

Chemical Name:
3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity:
≥98%
Potent, selective Src family kinase inhibitor
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #693010
Applications:
WB, Flow, ICC/IF, Simple Western, CyTOF-ready
Detection of Human Lck antibody by Western Blot.
(4)
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF
Lck Antibody - BSA Free Immunohistochemistry-Paraffin: Lck Antibody - BSA Free [NBP1-85804]
(7)
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #755216
Applications:
WB, ICC/IF
Detection of Human Phospho-Lck (Y505) antibody by Western Blot.
(2)

Highly potent pan-Src/Bcr-Abl inhibitor

Alternate Names:
BMS-354825
Chemical Name:
N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
Purity:
≥98%
Highly potent pan-Src/Bcr-Abl inhibitor
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #33D196
Applications:
WB
Western Blot: Lck Antibody (33D196)BSA Free [NB100-56678]
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #33D196
Applications:
WB
Western Blot: Lck Antibody (33D196)Azide and BSA Free [NBP2-80832]
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #355713
Applications:
ICC/IF
Lck antibody in Human PBMCs by Immunocytochemistry (ICC).
Reactivity:
Human
Source:
Sf 9 (baculovirus)
Accession #:
NM_005356
Applications:
Bioactivity
Recombinant Human Active Lck Protein SDS-PAGE
Reactivity:
Human, Mouse (Negative)
Details:
Mouse IgG1 Monoclonal Clone #LCK-01
Applications:
WB, Flow, ICC/IF, IP, CyTOF-ready
Western Blot: Lck Antibody (LCK-01)BSA Free [NB500-336]
(2)

Dual site Src kinase inhibitor

Chemical Name:
6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine
Purity:
≥98%
Dual site Src kinase inhibitor

Potent and selective Lck and Src inhibitor; also inhibits SIK

Alternate Names:
KIN112
Chemical Name:
2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate
Purity:
≥98%
Potent and selective Lck and Src inhibitor; also inhibits SIK

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #SR2027
Applications:
IHC, WB, Flow, ICC/IF, IP

Potent Lck inhibitor

Chemical Name:
6-(2,6-Dimethylphenyl)-2-[[4-(4-methyl-1-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one
Purity:
≥98%
Potent Lck inhibitor

Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

Chemical Name:
2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide
Purity:
≥95%
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

Chemical Name:
2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide
Purity:
≥95%
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

Potent and selective LCK Degrader (PROTAC®)

Chemical Name:
N-(2-Chloro-6-methylphenyl)-2-((6-(4-(3-(2-(4-(2,6-dioxopiperidin-3-yl)phenoxy)acetamido)propyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide
Purity:
≥98%
Potent and selective LCK Degrader (PROTAC®)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB
Western Blot: Lck [p Tyr394] Antibody [NBP3-13305]
(2)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB
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