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14 results for "Klotho beta" in Products
Klotho beta Products
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
Reactivity:
Mouse
Source:
NS0
Accession #:
NP_112457
Applications:
Bioactivity
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB
Reactivity:
Human
Source:
NS0
Accession #:
Q86Z14
Applications:
Bioactivity
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ICC/IF
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #885935
Applications:
WB, Simple Western
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #1025C
Applications:
Flow, ICC/IF
Reactivity:
Human
Source:
NS0
Accession #:
Q86Z14
Applications:
Bioactivity
Reactivity:
Cynomolgus Monkey
Reactivity:
Human
Details:
Rabbit Polyclonal
Applications:
IHC, WB
Reactivity:
Human
Details:
Mouse IgG2b Kappa Monoclonal Clone #8#
Applications:
WB
Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #RG7992
Applications:
ELISA, Flow, Func
Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #NGM313
Applications:
ELISA, Flow, Func
Reactivity:
Mouse
Assay Range:
15.6 - 1000 pg/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
15.625 - 1000 pg/mL (example only; lot dependent)
Applications:
ELISA