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Klotho beta Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09315

Novus Biologicals, part of Bio-Techne
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NBP3-09315-100ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free

Concentration

0.5 mg/ml

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human Klotho beta (NP_783864). Peptide sequence DAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQG

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit Klotho beta Antibody - BSA Free (NBP3-09315) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Klotho beta Antibody - BSA Free

Western Blot: Klotho beta Antibody [NBP3-09315]

Western Blot: Klotho beta Antibody [NBP3-09315]

Western Blot: Klotho beta Antibody [NBP3-09315] - Western blot analysis of Klotho beta in 721_B Whole Cell lysates. Antibody dilution at 0.5ug/ml

Applications for Klotho beta Antibody - BSA Free

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Klotho beta

Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to  FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.

Alternate Names

KLB

Gene Symbol

KLB

Additional Klotho beta Products

Product Documents for Klotho beta Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Klotho beta Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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