10 results for "JNK/c-jun Inhibitors Small Molecules and Peptides" in Products
JNK/c-jun Inhibitors: Small Molecules and Peptides
JNKs (c-Jun N-terminal kinases) are a group of mitogen-activated protein kinases (MAPKs), originally called stress activated protein kinases (SAPKs), because they are activated by a variety of environmental stresses. They are also activated in response to cytokines such as TNF-α and IL-1, and growth factors.
There are three isoforms of JNK; JNK1, JNK2 and JNK3. JNK1 and JNK2 are ubiquitously expressed, whilst JNK3 expression is limited to the brain, heart and testis. JNK phosphorylates a ...
Selective JNK inhibitor
| Chemical Name: | N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of JNK2 and JNK3
| Chemical Name: | N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide |
| Purity: | ≥98% (HPLC) |
TCS JNK 6o synthesized to Ancillary Material Grade
| Chemical Name: | N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide |
| Purity: | ≥98% |
Selective JNK inhibitor
| Chemical Name: | Anthra[1-9-cd]pyrazol-6(2H)-one |
| Purity: | ≥98% (HPLC) |
Inhibitor of JNK signaling
| Chemical Name: | (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester |
| Purity: | ≥97% (HPLC) |
Selective JNK inhibitor
| Alternate Names: | Halicin |
| Chemical Name: | 5-[(5-Nitro-2-thiazolyl)thio]-1,3,4thiadiazol-2-amine |
| Purity: | ≥98% (HPLC) |
Peptide inhibitor of JNK/c-Jun interaction
| Purity: | ≥95% (HPLC) |
Selective, competitive JNK inhibitor
| Chemical Name: | 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one |
| Purity: | ≥98% (HPLC) |
Highly potent and selective JNK3 inhibitor
| Chemical Name: | 3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)benzamide |
| Purity: | ≥97% (HPLC) |
High affinity JNK inhibitor; also inhibits HCMV replication
| Chemical Name: | 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride |
| Purity: | ≥98% (HPLC) |
