5 results for "Integrin alpha 4 beta 1 Small Molecules and Peptides" in Products
Integrin alpha 4 beta 1: Small Molecules and Peptides
Integrin alpha 4 beta 1, also known as VLA-4, is an Integrin family adhesion receptor that shares the beta 1 subunit with eleven other family members and the alpha 4 subunit with Integrin alpha 4 beta 7. The noncovalent heterodimer of alpha 4/CD49d and beta 1/CD29 subunits mediates cell adhesion to VCAM-1/CD106 on other cells and the CS-1 fragment of Fibronectin in the extracellular matrix. Leukocytes (except for neutrophils), erythroid precursors, and some non-hematopoietic cells such as ...
Highly potent and selective inhibitor of integrin α4β1 (VLA-4)
| Chemical Name: | (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid |
| Purity: | ≥98% (HPLC) |
Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable
| Chemical Name: | (αS)-α-[(2,6-Dichlorobenzoyl)amino]-2',6'-dimethoxy[1,1'-biphenyl]-4-propanoic acid |
| Purity: | ≥98% (HPLC) |
Selective α4β1 (VLA-4) inhibitor
| Purity: | ≥95% (HPLC) |
α4β1 (VLA-4) antagonist
| Chemical Name: | 1-[[(3S)-4-[2-[4-[[[(2-Methylphenyl)amino]carbonyl]amino]phenyl]acety]l-3-morpholinyl]carbonyl]-4-piperidinediacetic acid |
| Purity: | ≥98% (HPLC) |
α4β1 (VLA-4) ligand
| Purity: | ≥95% (HPLC) |
