4 results for "IMP Dehydrogenase 2/IMPDH2 Small Molecules and Peptides" in Products
IMP Dehydrogenase 2/IMPDH2: Small Molecules and Peptides
IMPDH2 encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
IMPDH2 (inosine monophosphate dehydrogenase 2) inhibitor, also glioblastoma targeting Nicotinamide mimetic prodrug
| Chemical Name: | N-3-Pyridinyl-2-thiophenecarboxamide |
| Purity: | ≥98% (HPLC) |
Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
| Chemical Name: | 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid |
| Purity: | ≥98% (HPLC) |
Inosine monophosphate dehydrogenase (IMPDH) inhibitor
| Chemical Name: | 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester |
| Purity: | ≥98% (HPLC) |
Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
| Chemical Name: | N-[1-[6-(4-Ethyl-1-piperazinyl)-3-pyridinyl]-1-methylethyl]-2-fluoro-9,10-dihydro-9-oxo-3-acridinecarboxamide |
| Purity: | ≥98% (HPLC) |
