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535 results for "IL-23" in Products

IL-23 Products

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

Source: Sf 21 (baculovirus)
Accession #: P29460 (p40) & AAG37232 (p19)
Applications: BA

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

The Mouse Cytokine Array, Panel A utilizes capture antibodies spotted onto a nitrocellulose membrane to allow high-throughput multi-analyte profiling of 40 cytokines, chemokines, and more in a single sample.
(3)

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.
(3)
Source: HEK293
Accession #: P29460.1 & AAG37232.1
Applications: BA
(2)
Sensitivity: 16.3 pg/mL
Applications: ELISA
Assay Range: 39 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Human IL-23 ELISA Standard Curve
(2)
Reactivity: Human
Details: Mouse IgG1 kappa Monoclonal Clone #eBio473P19 (eBio11P19, eBio25P19)
Applications: WB, ELISA
Novus Antibodies
Assay Range: 125 - 8,000 pg/mL
Applications: ELISA
Human IL-23 ELISA Standard Curve
Sensitivity: 4.17 pg/mL
Applications: ELISA
Assay Range: 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, Heparin Plasma)
Mouse IL-23 ELISA Standard Curve
(2)

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Applications: NULL
(2)

Analyzed by SEC-MALS

Source: CHO
Applications: BA
(2)
Reactivity: Human
Details: Goat IgG Polyclonal
Applications: WB, Neut
IL-17 Secretion Induced by IL-23 and Neutralization by Human IL-23 Antibody.
(2)

Analyzed by SEC-MALS.

Source: HEK293
Accession #: P43432.1 (p40) & Q9EQ14.1 (p19)
Applications: BA
(3)
Assay Range: 39.1 - 2,500 pg/mL
Applications: ELISA
Mouse IL-23 ELISA Standard Curve

Recombinant Monoclonal Antibody

Reactivity: Human
Details: Human IgG1 Monoclonal
Applications: ELISA, Flow, Func
IL-23A/IL-23 P19 Antibody (risankizumab) - Humanized
Source: Sf 21 (baculovirus)
Accession #: NP_072133 (p40) & NP_569094 (p19)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Reactivity: Mouse
Details: Goat IgG Polyclonal
Applications: WB, Neut
IL‑17 secretion Induced by IL‑23 and Neutralization by Mouse IL‑23 Antibody.
Reactivity: Mouse
Details: Rat IgG2a Monoclonal Clone #320229
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