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IL-12/IL-23 p40 Products

IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.

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496 results for "IL-12/IL-23 p40" in Products

496 results for "IL-12/IL-23 p40" in Products

IL-12/IL-23 p40 Products

IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.

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Sensitivity: 2.7 pg/mL
Applications: ELISA
Assay Range: 11.7 - 750 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Mouse IL-12/IL-23 p40 Non Allele-specific ELISA Standard Curve
(2)
Sensitivity: 4 pg/mL
Applications: ELISA
Assay Range: 11.7 - 750 pg/mL (Cell Culture Supernates, Serum)
Mouse IL-12/IL-23 p40 Allele-specific ELISA Standard Curve
(2)
Sensitivity: 15 pg/mL
Applications: ELISA
Assay Range: 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
Human IL-12/IL-23 p40 Homodimer ELISA Cell Culture Supernate Standard Curve
(3)
Assay Range: 31.2 - 2,000 pg/mL
Applications: ELISA
Mouse IL-12 / IL-23 p40 ELISA Standard Curve
Assay Range: 62.5 - 4,000 pg/mL
Applications: ELISA
Human IL-12 / IL-23 p40 ELISA Standard Curve
Sensitivity: 18.2 pg/mL
Applications: ELISA
Assay Range: 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
Porcine IL-12/IL-23 p40 ELISA Calibrator Diluent RD5Y Standard Curve
(3)
Source: Sf 21 (baculovirus)
Accession #: P29460
Applications: BA
Recombinant Human IL-12/IL-23 p40 Monomer Protein Binding Activity

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Detection of selected mouse cytokines in Balb/3T3 Cell Line Lysate
(3)
Source: Sf 21 (baculovirus)
Accession #: P43432.1
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Assay Range: 15.6 - 1,000 pg/mL
Applications: ELISA
Mouse IL-12 / IL-23 p40 Non Allele-specific ELISA Standard Curve
Reactivity: Mouse
Details: Goat IgG Polyclonal
Applications: WB
Assay Range: 78.1 - 5,000 pg/mL
Applications: ELISA
Porcine IL-12 / IL-23 p40 ELISA Standard Curve
Assay Range: 62.5 - 4,000 pg/mL
Applications: ELISA
Canine IL-12 / IL-23 p40 ELISA Standard Curve
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