Histamine H4R: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G protein-coupled receptor superfamily. Histamine H4R is a histamine receptor that is predominantly expressed in hematopoietic cells. Histamine H4R is thought to play a role in inflammation and allergy responses.
Products:
7 results for "Histamine H4R Small Molecules and Peptides" in Products
7 results for "Histamine H4R Small Molecules and Peptides" in Products
Histamine H4R: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G protein-coupled receptor superfamily. Histamine H4R is a histamine receptor that is predominantly expressed in hematopoietic cells. Histamine H4R is thought to play a role in inflammation and allergy responses.
Products:
Endogenous histamine receptor agonist
| Chemical Name: | 2-(4-Imidazolyl)ethylamine dihydrochloride |
H3 antagonist; also H4 inverse agonist
| Chemical Name: | N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
High affinity and selective histamine H4 antagonist; orally bioavailable
| Chemical Name: | 4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective, high affinity H4 agonist
| Chemical Name: | 5-(2-Aminoethyl)-4-methylimidazole dihydrochloride |
Selective H4 antagonist
| Chemical Name: | 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine |
| Purity: | ≥98% (HPLC) |
Selective H4 antagonist; orally active
| Alternate Names: | VUF 6002 |
| Chemical Name: | 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate |
| Purity: | ≥98% (HPLC) |
