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HGFR/c-MET Products

HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron.

Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.

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852 results for "HGFR/c-MET" in Products

852 results for "HGFR/c-MET" in Products

HGFR/c-MET Products

HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron.

Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.

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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #95106
Applications: Flow, CyTOF-ready
Detection of HGF R/c-MET antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #95106
Applications: Flow
Detection of HGF R/c-MET antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, Simple Western, IHC, CyTOF-reported, ICC, +1 More
Detection of Human Phospho-HGF R/c-MET (Y1234/Y1235) antibody by Western Blot.
(7)
Source: NS0
Accession #: P08581
Applications: Bind
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #95106
Applications: Flow
Detection of HGF R/c-MET antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
(2)

Simple Plex Human HGFR/c-MET assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Simple Plex
Human HGF R Simple Plex Assy
(3)

Control for use with Human HGFR/c-MET Simple Plex Cartridge Kit

Applications: Ctrl, Simple Plex
Assay Range: 62.5 - 4,000 pg/mL
Applications: ELISA
Human HGF R / c-MET ELISA Standard Curve
Applications: ELISA
(3)

Recombinant Monoclonal Antibody

Reactivity: Human
Details: Human IgG4 Monoclonal
Applications: ELISA, Flow, Func
HGFR/c-MET Antibody (emibetuzumab) - Humanized, IgG4SP
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, IHC, ICC
Detection of Human Phospho-HGF R/ c-MET (Y1349) antibody by Western Blot.
(3)
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #95106
Applications: Flow
Detection of HGF R/c-MET antibody in MDA-MB-231 Human Cell Line antibody by Flow Cytometry.
Source: HEK293
Accession #: EHH52447.1
Applications: BA
(2)
Source: NS0
Accession #: Q75ZY9
Applications: Bind
R&D Systems Recombinant Proteins and Enzymes
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