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13 results for "GABA-A R alpha 1 Small Molecules and Peptides" in Products

GABA-A R alpha 1 Small Molecules and Peptides

GABA A (γ-aminobutyric acid-type A) receptors are members of the cysteine-loop family of neurotransmitter-gated ion channels. GABA binding to A-type receptors induces anion-selective ion channel opening. These receptors are the principal fast inhibitory neurotransmitter receptors in the CNS. GABA A receptors are heteropentamer combinations of seven subunit types; α, β, γ, δ, ε, θ, and π. Three subunits, α, β, and γ, have at least ...

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Competitive and selective GABAA antagonist

Alternate Names:
Gabazine
Chemical Name:
6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide
Purity:
≥98%
Competitive and selective GABAA antagonist

Potent GABAA agonist; also GABAA-ρ partial agonist

Chemical Name:
5-Aminomethyl-3-hydroxyisoxazole
Purity:
≥98%
Potent GABAA agonist; also GABAA-ρ partial agonist

Benzodiazepine partial inverse agonist

Chemical Name:
8-Azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester
Purity:
≥98%
Benzodiazepine partial inverse agonist

CNS stimulant

Alternate Names:
PTZ
Chemical Name:
6,7,8,9-Tetrahydro-5H-tetrazolo[1,5-a]azepine
Purity:
≥98%
CNS stimulant

Benzodiazepine inverse agonist

Chemical Name:
N-Methyl-β-carboline-3-carboxamide
Purity:
≥99%
Benzodiazepine inverse agonist

GABAA agonist

Alternate Names:
Gaboxadol
Chemical Name:
4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride
Purity:
≥98%
GABAA agonist

Positive allosteric modulator of GABAA receptors

Alternate Names:
3a,5a-THPROG
Chemical Name:
(3α,5α)-3-Hydroxy-pregnan-20-one
Positive allosteric modulator of GABAA receptors

Benzodiazepine antagonist

Alternate Names:
Ro 15-1788
Chemical Name:
8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester
Purity:
≥99%
Benzodiazepine antagonist

Benzodiazepine inverse agonist

Chemical Name:
4-Ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester hydrochloride
Purity:
≥98%
Benzodiazepine inverse agonist

GABAA partial agonist; displays subtype selectivity

Chemical Name:
3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine
Purity:
≥98%
GABAA partial agonist; displays subtype selectivity

Postitive allosteric modulator of GABAA receptors

Chemical Name:
(3α,5β)-3-Hydroxy-pregnan-20-one
Postitive allosteric modulator of GABAA receptors

α5-selective GABAA inverse agonist

Chemical Name:
6,7-Dihydro-3-[(2-hydroxyethyl)thio]-6,6-dimethyl-1-(2-thiazolyl)-benzo[c]thiophen-4(5H)-one
Purity:
≥98%
α5-selective GABAA inverse agonist

Postitive allosteric modulator of GABAA receptors

Chemical Name:
(3α,5β)-3-Hydroxy-pregnan-20-one
Postitive allosteric modulator of GABAA receptors
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