19 results for "Cytokine Compounds Small Molecules and Peptides" in Products
Cytokine Compounds: Small Molecules and Peptides
Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases.
Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune ...
Antifibrotic agent; regulates cytokine levels in vivo
| Chemical Name: | 5-methyl-1-phenyl-2(1H)-pyridinone |
| Purity: | ≥98% (HPLC) |
Binds cereblon; also TNF-α synthesis inhibitor
| Chemical Name: | N-(2,6-dioxo-3-piperidinyl)phthalimide |
| Purity: | ≥98% (HPLC) |
Selective Syk kinase inhibitor
| Chemical Name: | 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate |
| Purity: | ≥98% (HPLC) |
Macrophage migration inhibitory factor (MIF) inhibitor
| Chemical Name: | 4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester |
| Purity: | ≥98% (HPLC) |
Immunomodulatory and antitumor compound
| Chemical Name: | 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone |
| Purity: | ≥98% (HPLC) |
Immunomodulator; reduces production of pro-inflammatory cytokines
| Chemical Name: | 4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid |
| Purity: | ≥98% (HPLC) |
Suppressor of MDK expression; inhibits PI 3-K signaling
| Chemical Name: | 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one |
| Purity: | ≥98% (HPLC) |
Active metabolite binds CPSF3; Pro-drug
| Alternate Names: | TO-207 |
| Chemical Name: | N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride |
| Purity: | ≥98% (HPLC) |
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
| Chemical Name: | 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione |
| Purity: | ≥98% (HPLC) |
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
| Chemical Name: | 4-Iodo-6-phenylpyrimidine |
| Purity: | ≥98% (HPLC) |
Cereblon binder; also TNF-α inhibitor and antiangiogenic
| Chemical Name: | 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione |
| Purity: | ≥98% (HPLC) |
TIR-TIR interaction inhibitor
| Chemical Name: | 1-Methyl-2,5-bis[[[(1S)-2-methyl-1-(1-pyrrolidinylcarbonyl)propyl](3-phenylpropyl)amino]carbonyl]pyridinium iodide |
| Purity: | ≥98% (HPLC) |
gp130 agonist; brain penetrant and neuroprotectant
| Chemical Name: | N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine |
| Purity: | ≥98% (HPLC) |
Potent NLRP3 inflammasome inhibitor
| Chemical Name: | 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione |
| Purity: | ≥95% (HPLC) |
MIF binder
| Chemical Name: | 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one |
| Purity: | ≥98% (HPLC) |
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
| Alternate Names: | FOY |
| Chemical Name: | 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester mesylate |
| Purity: | ≥98% (HPLC) |
NLRP3 inflammasome inhibitor
| Alternate Names: | JC121 |
| Chemical Name: | N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective IRAK4 inhibitor
| Chemical Name: | N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
TRAF6-Ubc13 interaction inhibitor
| Chemical Name: | 3-[3,5-Dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-propanone |
| Purity: | ≥98% (HPLC) |
