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beta-Catenin Products

beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.

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752 results for "beta-Catenin" in Products

752 results for "beta-Catenin" in Products

beta-Catenin Products

beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.

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Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins

Detection of human protein kinase phosphorylation in A549 Cell Line.
(4)

Potent tankyrase inhibitor

Alternate Names: XAV939 Wnt Signaling Inhibitor
Chemical Name: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity: ≥98% (HPLC)
Potent tankyrase inhibitor
Reactivity: Human, Mouse, Rat, Primate, Chicken, +3 More
Details: Mouse IgG1 Monoclonal Clone #12F7
Applications: IHC, WB, ICC/IF, Flow, IP, +1 More
Western Blot: beta-Catenin Antibody (12F7)BSA Free [NBP1-54467]
(12)
Reactivity: Human, Mouse, Rat, Canine, Zebrafish, +2 More
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, Flow, IP, +2 More
Western Blot: beta-Catenin Antibody [NBP1-32239]
(43)

XAV 939 synthesized to cGMP guidelines

Chemical Name: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity: ≥99%
XAV 939 synthesized to cGMP guidelines
Assay Range: 312 - 20,000 pg/mL
Applications: ELISA
Reactivity: Human, Mouse, Rat, Primate, Chicken, +1 More
Details: Mouse IgG1 Monoclonal Clone #12F7
Applications: IHC, WB, ICC/IF, Flow, IP, +2 More
Western Blot: beta-Catenin Antibody (12F7)Azide and BSA Free [NBP2-80596]
(11)

Inhibits TCF/β-catenin-mediated transcription

Chemical Name: (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
Purity: ≥98% (HPLC)
Inhibits TCF/β-catenin-mediated transcription

Potent inhibitor of Wnt/β-catenin signaling

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity: ≥98% (HPLC)
Potent inhibitor of Wnt/β-catenin signaling

Inhibits β-catenin-responsive transcription (CRT)

Chemical Name: 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedion
Purity: ≥98% (HPLC)
Inhibits β-catenin-responsive transcription (CRT)

Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions

Purity: ≥95% (HPLC)
Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions

Frizzled 4 allosteric agonist; exhibits biased signaling; preserves stemness

Chemical Name: 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid
Purity: ≥98% (HPLC)
Frizzled 4 allosteric agonist; exhibits biased signaling; preserves stemness

β-catenin binder; inhibits Wnt signaling

Chemical Name: 2-Phenoxybenzoic acid-[(5-methyl-2-furanyl)methylene]hydrazide
Purity: ≥98% (HPLC)
β-catenin binder; inhibits Wnt signaling

Selective peptide-based β-catenin Degrader (PROTAC®)

Purity: ≥95% (HPLC)
Selective peptide-based β-catenin Degrader (PROTAC®)

Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma

Chemical Name: 4-[3-Fluoro-4-[[[[4-(1,1,2,2,2-pentafluoroethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Purity: ≥98% (HPLC)
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
Reactivity: Human, Mouse, Rat, Fish
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Immunocytochemistry/ Immunofluorescence: beta-Catenin Antibody [NBP1-89989]
(10)

Wnt/β-catenin signaling inhibitor

Purity: ≥90% (HPLC)
Wnt/β-catenin signaling inhibitor

Inhibitor of Wnt/β-catenin signaling

Chemical Name: N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2H-1-benzopyran-3-carboxamide
Purity: ≥98% (HPLC)
Inhibitor of Wnt/β-catenin signaling
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