beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
671 results for "beta-Catenin" in Products
671 results for "beta-Catenin" in Products
beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ChIP, CyTOF-ready, +2 More |
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Primate, Chicken, +3 More |
| Details: | Mouse IgG1 Monoclonal Clone #12F7 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
![Western Blot: beta-Catenin Antibody (12F7)BSA Free [NBP1-54467]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-12F7-Western-Blot-NBP1-54467-img0008.jpg "Western Blot: beta-Catenin Antibody (12F7)BSA Free [NBP1-54467]")
| Reactivity: | Human, Mouse, Rat, Canine, Zebrafish, +2 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
![Western Blot: beta-Catenin Antibody [NBP1-32239]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-Western-Blot-NBP1-32239-img0033.jpg "Western Blot: beta-Catenin Antibody [NBP1-32239]")
Inhibits β-catenin-responsive transcription (CRT)
| Chemical Name: | 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedion |
| Purity: | ≥98% (HPLC) |
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
Potent inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity: | ≥98% (HPLC) |
| Assay Range: | 312 - 20,000 pg/mL |
| Applications: | ELISA |
Inhibits TCF/β-catenin-mediated transcription
| Chemical Name: | (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide |
| Purity: | ≥98% (HPLC) |
Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions
| Purity: | ≥95% (HPLC) |
Selective peptide-based β-catenin Degrader (PROTAC®)
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG3 Monoclonal Clone #196618 |
| Applications: | WB, IHC, ICC |
β-catenin binder; inhibits Wnt signaling
| Chemical Name: | 2-Phenoxybenzoic acid-[(5-methyl-2-furanyl)methylene]hydrazide |
| Purity: | ≥98% (HPLC) |
Inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2H-1-benzopyran-3-carboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Primate, Chicken, +1 More |
| Details: | Mouse IgG1 Monoclonal Clone #12F7 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
![Western Blot: beta-Catenin Antibody (12F7)Azide and BSA Free [NBP2-80596]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-12F7-Azide-and-BSA-Free-Western-Blot-NBP2-80596-img0004.jpg "Western Blot: beta-Catenin Antibody (12F7)Azide and BSA Free [NBP2-80596]")
Wnt/β-catenin signaling inhibitor
| Purity: | ≥90% (HPLC) |
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
| Chemical Name: | 4-[3-Fluoro-4-[[[[4-(1,1,2,2,2-pentafluoroethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Frizzled 4 allosteric agonist; exhibits biased signaling; preserves stemness
| Chemical Name: | 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #196621 |
| Applications: | WB, IHC, mIF |
endo-IWR 1 synthesized to Ancillary Material Grade
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
| Applications: | PAGE, Bioactivity |
| Reactivity: | Human, Mouse, Rat, Fish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: beta-Catenin Antibody [NBP1-89989]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-89989-img0011.jpg "Immunocytochemistry/ Immunofluorescence: beta-Catenin Antibody [NBP1-89989]")