AMPK alpha 1 Products
AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic a subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms (alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations capable of forming complexes. The catalytic a subunit of AMPK is activated allosterically by AMP and by phosphorylation via the AMPK kinase LKB1. Active AMPK downregulates anabolic pathways such as fatty acid, triglyceride, and cholesterol synthesis, and up-regulates catabolic pathways such as glycolysis and fatty acid oxidation. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.
166 results for "AMPK alpha 1" in Products
166 results for "AMPK alpha 1" in Products
AMPK alpha 1 Products
AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic a subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms (alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations capable of forming complexes. The catalytic a subunit of AMPK is activated allosterically by AMP and by phosphorylation via the AMPK kinase LKB1. Active AMPK downregulates anabolic pathways such as fatty acid, triglyceride, and cholesterol synthesis, and up-regulates catabolic pathways such as glycolysis and fatty acid oxidation. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #2B7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Simple Western: AMPK alpha 1 Antibody (2B7)BSA Free [NBP2-22127]](https://resources.bio-techne.com/images/products/AMPK-alpha-1-Antibody-2B7-Simple-Western-NBP2-22127-img0006.jpg "Simple Western: AMPK alpha 1 Antibody (2B7)BSA Free [NBP2-22127]")
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #2B7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
![AMPK alpha 1 Antibody (2B7) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-22127cl1_mouse-ampk-alpha-1-mab-2b7-corafluor-1-24920251656131.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: AMPK alpha 1 Antibody [NB100-239]](https://resources.bio-techne.com/images/products/AMPK-alpha-1-Antibody-Western-Blot-NB100-239-img0006.jpg "Western Blot: AMPK alpha 1 Antibody [NB100-239]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![AMPK alpha 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nb100-239cl1_rabbit-ampk-alpha-1-pab-corafluor-1-89202516495217.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![AMPK alpha 1 Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af3197cl1_goat-ampk-alpha-1-pab-corafluor-1-12920251042125.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #362532 |
| Applications: | WB, ICC/IF |
| Assay Range: | 625 - 40,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #2B7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
![Western Blot: AMPK alpha 1 Antibody (2B7)Azide and BSA Free [NBP2-80575]](https://resources.bio-techne.com/images/products/AMPK-alpha-1-Antibody-2B7-Azide-and-BSA-Free-Western-Blot-NBP2-80575-img0001.jpg "Western Blot: AMPK alpha 1 Antibody (2B7)Azide and BSA Free [NBP2-80575]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, Simple Western, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: AMPK alpha 1 [p Ser496] Antibody [NB100-81784]](https://resources.bio-techne.com/images/products/AMPK-alpha-1-[p-Ser496]-Antibody-Western-Blot-NB100-81784-img0016.jpg "Western Blot: AMPK alpha 1 [p Ser496] Antibody [NB100-81784]")
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #362532 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |