AICAR

Tocris Bioscience, part of Bio-Techne | Catalog # 2840

AMPK activator
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Key Product Details

Description

AMPK activator

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Product Description

AICAR is a cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCs in vitro.

Product Specifications

Molecular Weight

258.23

Formula

C9H14N4O5

Storage

Store at -20°C

Purity

≥99% (HPLC)

Chemical Name

N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide

CAS Number

2627-69-2

PubChem ID

17513

InChI Key

RTRQQBHATOEIAF-UUOKFMHZSA-N

SMILES

O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC(C(N)=O)=C2N)[C@@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 19.37 75
DMSO 19.37 75

Preparing Stock Solutions for AICAR

The following data is based on the product molecular weight 258.23

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 5.16 mL 25.82 mL 51.63 mL
3.75 mM 1.03 mL 5.16 mL 10.33 mL
7.5 mM 0.52 mL 2.58 mL 5.16 mL
37.5 mM 0.10 mL 0.52 mL 1.03 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Product Documents for AICAR

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AICAR

For research use only

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