8 results for "Additional NMDA Receptor Compounds Small Molecules and Peptides" in Products
Additional NMDA Receptor Compounds: Small Molecules and Peptides
NMDA receptors are expressed alongside AMPA receptors on the postsynaptic membrane of excitatory synapses, where they initiate a two-component excitatory postsynaptic potential (EPSP). The activation of AMPA receptors produces a current that has rapid onset and decay, while activation of NMDA receptors leads to a current with slower onset and decay. The slow decay of NMDA-mediated currents is due to the slow dissociation of glutamate from NMDA receptors, compared with AMPA receptors. Unlike ...
Endogenous potentiator of NMDA receptors
| Chemical Name: | Aminoethanoic acid |
Potentiator of NMDA receptors containing GluN2C/GluN2D
| Chemical Name: | (3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone |
| Purity: | ≥98% (HPLC) |
NMDA potentiator; also GABAA inhibitor and TRPM3 activator
| Chemical Name: | (3β)-3-(Sulfooxy)-pregn-5-en-20-one sodium salt |
Potentiator of NMDA recepors; acts at glycine site
Open-channel blocker of AMPA currents; selective for non-GluA2-containing receptors
| Chemical Name: | N,N,H,-Trimethyl-5-[(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide |
| Purity: | ≥98% (HPLC) |
Modulator at polyamine site
| Chemical Name: | N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride |
Enhances AMPA currents: antidepressant
| Chemical Name: | cis-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Cognitive enhancer
| Alternate Names: | DM 9384 |
| Chemical Name: | N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide |
| Purity: | ≥99% (HPLC) |
