SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26919
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
SARS-CoV-2
Applications
ELISA
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Human IgG1 Clone # CR3022 expressed in CHO
Format
Azide and BSA Free
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant SARS-CoV-2 Spike S1 Protein
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Description
Novus Biologicals Human SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free (NBP3-26919) is a recombinant monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free
Western Blot: SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free [NBP3-26919] -
Western Blot: SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free [NBP3-26919] - Coomassie blue staining non-reduced and reduced SDS-PAGE analysis
ELISA: SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free [NBP3-26919] -
ELISA: SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free [NBP3-26919] - Sandwich ELISA for SARS-CoV-2 Matched Pair Spike S1 Antibodies. Antibodies: SARS-CoV-2 Spike Antibodies, NBP3-07065 and NBP3-26919. A sandwich ELISA was performed using SARS-CoV-2 Spike S1 antibody (NBP3-07065, 2ug/ml) as capture antibody, the Spike S1 recombinant protein as the binding protein, and the anti-SARS-CoV-2 Spike S1 protein antibody (NBP3-26919, 1ug/ml) as the detection antibody. Secondary: Mouse anti-human IgG HRP conjugate at 1:10000 dilution. Detection range is from 0.03 ng to 300 ng. EC50 = 1.58 ng.Applications for SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free
Application
Recommended Usage
ELISA
1:5000-1:10000
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS (pH 7.5)
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Spike S1 Subunit
Spike S1 subunit refers to the N-terminal part of the coronavirus Spike protein. The S1 subunit contains an N-terminal domain in addition to the much-studied receptor binding domain (RBD). Spatially, the S1 subunit represents the most membrane-distal portion of the spike protein. For SARS-CoV-2, this subunit, specifically the RBD domain, is responsible for binding to ACE-2 on the surface of human cells and initiating viral entry. Because this interaction is so important for viral entry into host cells, the RBD domain has been the focus of therapeutic and vaccine development for COVID-19. The N-terminal domain of the S1 subunit may also be involved in receptor binding independent of ACE-2. Current research is underway to better understand this domain as it may unlock new therapeutic strategies to fight SARS-CoV-2.
Long Name
Spike Protein, S1 Subunit
Alternate Names
SARS-CoV-2
Additional Spike S1 Subunit Products
Product Documents for SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free
Product Specific Notices for SARS-CoV-2 Spike S1 Protein Antibody (CR3022) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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