MGC20410 Antibody (PCRP-BATF2-2B9) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20913JF646

Novus Biologicals, part of Bio-Techne
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NBP3-20913JF646
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunohistochemistry-Paraffin, Immunoprecipitation

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # PCRP-BATF2-2B9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MGC20410 Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa5-140) of human MGC20410 (exact sequence is proprietary)

Localization

Nucleus.

Specificity

This antibody recognizes a transcription factor involved in differentiation of CD8+ thymic dendritic cells MGC20410 has been implicated in breast cancer, malignant glioma and metastatis melanoma progression

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for MGC20410 Antibody (PCRP-BATF2-2B9) [Janelia Fluor® 646]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MGC20410

BATF2 (Basic leucine zipper transcriptional factor ATF-like 2) is a 274 amino acid member of the AP-1 transcription factor family. It controls the differentiation of lineage-specific cells in the immune system. It participates in differentiating CD8+ thymic conventional dendritic cells and acts by forming a heterodimer with JUN family proteins. They then recognize and bind the DNA sequence 5'-TGA(CG)TCA-3'. It acts as a tumor suppressor by interfering with AP-1 regulated activation of CYR61/CCN1 transcription and its downstream signaling. CYR61/CCN1 signaling induces anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma.

Alternate Names

basic leucine zipper transcription factor, ATF-like 2, basic leucine zipper transcriptional factor ATF-like 2, B-ATF-2, MGC20410, SARI, suppressor of AP-1 regulated by IFN

Gene Symbol

BATF2

Additional MGC20410 Products

Product Documents for MGC20410 Antibody (PCRP-BATF2-2B9) [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MGC20410 Antibody (PCRP-BATF2-2B9) [Janelia Fluor® 646]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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