Carboxymethyl Lysine Antibody (318003) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # FAB3247J
Conjugate
Catalog #
Key Product Details
Species Reactivity
Multi-Species
Applications
Western Blot
Label
Janelia Fluor 646
Antibody Source
Monoclonal Mouse IgG2B Clone # 318003
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Carboxymethyl Lysine-modified Keyhole Limpet Hemocyanin (KLH)
Specificity
Detects Carboxymethyl Lysine adducts on proteins in Western blots. In Western blots, no cross-reactivity with carboxyethyl lysine adducts is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Carboxymethyl Lysine Antibody (318003) [Janelia Fluor® 646]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Carboxymethyl Lysine
Carboxymethyl Lysine (CML) is an advanced glycation end product found on proteins and lipids as a result of oxidative stress and chemical glycation. CML adducts accumulate with aging and in several pathologies including Alzheimers disease, diabetes, and uremia. CML-modified proteins are recognized by the receptor RAGE which is expressed on a variety of cells.
Alternate Names
CML
Additional Carboxymethyl Lysine Products
Product Documents for Carboxymethyl Lysine Antibody (318003) [Janelia Fluor® 646]
Product Specific Notices for Carboxymethyl Lysine Antibody (318003) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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