7 results for "VEGFR1/Flt-1" in Products
VEGFR1/Flt-1 Products
VEGFR1 (vascular endothelial growth factor receptor 1; Flt-1) binds to VEGF-A, VEGF-B, and PlGF and functions in vasculogenesis, angiogenesis, lymphangiogenesis, and wound healing. It is expressed on endothelial cells, osteoblasts, placental trophoblasts, renal mesangial cells, and some hematopoietic stem cells. It can heterodimerize with VEGFR2 and modulate VEGFR2 mediated endothelial cell proliferation and vessel branching. VEGFR1 engagement on monocyte/macrophage lineage cells enhances their migration, and release of growth factors and cytokines.
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
Potent VEGFR-1, -2 and -3 inhibitor
Potent VEGFR, PDGFRβ and KIT inhibitor
Potent EGFR and VEGFR inhibitor
Potent VEGFR inhibitor; also aromatase inhibitor
Potent multi-kinase and pan-Bcr-Abl inhibitor
Inhibitor of Wnt/β-catenin signaling
