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8 results for "uPAR" in Products
uPAR Products
The urokinase-type Plasminogen Activator Receptor (uPAR) is a GPI-anchored protein that binds to both the inactive and active forms of uPA. This interaction serves to localize and enhance the proteolytic activity of uPA, leading to increased conversion of Plasminogen to Plasmin. uPA also triggers uPAR-mediated signal transduction, activation of protein tyrosine kinases, gene expression, cell adhesion, and chemotaxis. uPAR can additionally regulate cell adhesion by direct binding to Vitronectin and preventing Integrins from binding to their ligands.
Reactivity:
Human
Assay Range:
62.5-4000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine)
Applications:
ELISA
Reactivity:
Human
Assay Range:
4.69-300 pg/ml (example only; lot dependent)
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #62022
Applications:
WB, ELISA, ELISA(Cap), ELISA(Det), B/N, + 2 More
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N, Flow, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N, IP
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #109801
Applications:
WB, B/N, Flow, CyTOF-ready
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #ATN-658
Applications:
ELISA, Flow, Func
Reactivity:
Mouse
Details:
Rabbit IgG Monoclonal Clone #014
Applications:
ELISA