Smad7 Products
Smads are a family of intracellular proteins that mediate signaling by members of the TGF-beta superfamily. Smads are divided into three distinct subgroups based on their different roles in TGF-beta family signal transduction: R-Smads (receptor-regulated), Co-Smads (common partner), and I-Smads (inhibitory). In general, activation of TGF-beta superfamily serine/threonine kinase receptors leads to the phosphorylation of R-Smads (Smads1, 2, 3, 5, and 8). This is followed by recruitment of the Co-Smad (Smad-4) into an R-Smad/Co-Smad complex that translocates to the nucleus to regulate gene expression. I-Smads (Smad6 and Smad7) antagonize this signaling pathway by preventing R-Smads from interacting with the receptor, or by competing with Co-Smads for the generation of R-Smad/Co-Smad complexes.
117 results for "Smad7" in Products
117 results for "Smad7" in Products
Smad7 Products
Smads are a family of intracellular proteins that mediate signaling by members of the TGF-beta superfamily. Smads are divided into three distinct subgroups based on their different roles in TGF-beta family signal transduction: R-Smads (receptor-regulated), Co-Smads (common partner), and I-Smads (inhibitory). In general, activation of TGF-beta superfamily serine/threonine kinase receptors leads to the phosphorylation of R-Smads (Smads1, 2, 3, 5, and 8). This is followed by recruitment of the Co-Smad (Smad-4) into an R-Smad/Co-Smad complex that translocates to the nucleus to regulate gene expression. I-Smads (Smad6 and Smad7) antagonize this signaling pathway by preventing R-Smads from interacting with the receptor, or by competing with Co-Smads for the generation of R-Smad/Co-Smad complexes.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, Simple Western, IHC |
| Reactivity: | Human, Mouse, Sheep, Ovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, IP |
![Western Blot: Smad7 Antibody [NBP2-24710]](https://resources.bio-techne.com/images/products/Smad7-Antibody-Western-Blot-NBP2-24710-img0005.jpg "Western Blot: Smad7 Antibody [NBP2-24710]")
| Reactivity: | Human, Mouse, Sheep |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Smad7 AntibodyAzide Free [NB100-56688]](https://resources.bio-techne.com/images/products/Smad7-Antibody---Azide-Free-Western-Blot-NB100-56688-img0004.jpg "Western Blot: Smad7 AntibodyAzide Free [NB100-56688]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Smad7 Antibody [NBP1-87728]](https://resources.bio-techne.com/images/products/Smad7-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-87728-img0012.jpg "Immunocytochemistry/ Immunofluorescence: Smad7 Antibody [NBP1-87728]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #293039 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Smad7 Antibody [NBP3-13375]](https://resources.bio-techne.com/images/products/Smad7-Antibody-Western-Blot-NBP3-13375-img0002.jpg "Western Blot: Smad7 Antibody [NBP3-13375]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Smad7 AntibodyAzide and BSA Free [NBP2-93969]](https://resources.bio-techne.com/images/products/Smad7 "Western Blot: Smad7 AntibodyAzide and BSA Free [NBP2-93969]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3G8 |
| Applications: | WB, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Smad7 Antibody (3G8) [H00004092-M01]](https://resources.bio-techne.com/images/products/Smad7-Antibody-3G8-Immunocytochemistry-Immunofluorescence-H00004092-M01-img0003.jpg "Immunocytochemistry/ Immunofluorescence: Smad7 Antibody (3G8) [H00004092-M01]")
| Applications: | WB, ELISA, MA, AP |
![SDS-PAGE: Recombinant Human Smad7 GST (N-Term) Protein [H00004092-Q01]](https://resources.bio-techne.com/images/products/Recombinant-Human-Smad7-Protein-SDS-Page-H00004092-Q01-img0002.jpg "SDS-PAGE: Recombinant Human Smad7 GST (N-Term) Protein [H00004092-Q01]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Smad7 AntibodyBSA Free [NBP2-94158]](https://resources.bio-techne.com/images/products/Smad7-Antibody-Western-Blot-NBP2-94158-img0002.jpg "Western Blot: Smad7 AntibodyBSA Free [NBP2-94158]")
![Western Blot: Smad7 Overexpression Lysate [NBP2-07689]](https://resources.bio-techne.com/images/products/SMAD7-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07689-img0001.jpg "Western Blot: Smad7 Overexpression Lysate [NBP2-07689]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #293039 |
| Applications: | IHC, WB |