Skip to main content
Select a category to see relevant filters and products

107 results for "S1P1/EDG-1" in Products

S1P1/EDG-1 Products

EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family regulates essential cellular processes such as proliferation, migration, cytoskeletal organization, and differentiation.

Clone 218713 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #218713
Applications:
Flow, CyTOF-ready
Detection of S1P1/EDG-1 antibody in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
(2)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
IHC, Flow, CyTOF-ready
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected With S1P1/EDG-1 antibody by Flow Cytometry.
(4)
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF, IP
Western Blot: S1P1/EDG-1 Antibody [NB120-11424]
(8)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in Mouse Thymocytes antibody by Flow Cytometry.
(2)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected with Mouse S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
(2)

Recombinant Monoclonal Antibody

Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #JM10-66
Applications:
IHC, WB, Flow, ICC/IF
Western Blot: S1P1/EDG-1 Antibody (JM10-66) [NBP2-67129]
(11)

Endogenous agonist at S1P1-5

Chemical Name:
(E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol
Purity:
≥98%
Endogenous agonist at S1P1-5

Selective S1P1 agonist

Chemical Name:
1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid
Purity:
≥97%
Selective S1P1 agonist
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected with Mouse S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
(2)
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC
Immunohistochemistry-Paraffin: S1P1/EDG-1 Antibody [NBP2-27291]

Potent S1P receptor agonist; also immunosuppressant

Alternate Names:
Fingolimod,Gilenya
Chemical Name:
2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride
Purity:
≥98%
Potent S1P receptor agonist; also immunosuppressant

Clone 218713 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #218713
Applications:
Flow
Detection of S1P1/EDG-1 antibody in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #713412
Applications:
Flow
Detection of S1P1/EDG-1 antibody in HEK293 Human Cell Line Transfected with Mouse S1P1/EDG-1 and GFP antibody by Flow Cytometry.
(2)

Cell-permeable, selective S1P1 receptor agonist

Chemical Name:
5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]1,2,4-oxadiazole
Purity:
≥98%
Cell-permeable, selective S1P1 receptor agonist
Reactivity:
Mouse
R&D Systems VersaClone cDNA Plasmids

Selective S1P1 receptor agonist

Chemical Name:
2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride
Purity:
≥98%
Selective S1P1 receptor agonist

Potent and selective S1P1 receptor antagonist

Alternate Names:
ML 056
Chemical Name:
[(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid
Purity:
≥98%
Potent and selective S1P1 receptor antagonist

S1P1 and S1P3 antagonist

Chemical Name:
2-Amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamaide
Purity:
≥95%
S1P1 and S1P3 antagonist

Potent S1P1 agonist

Chemical Name:
N-[4-[5-[3-Cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine hydrochloride
Purity:
≥98%
Potent S1P1 agonist

Potent and selective S1P1 receptor antagonist

Chemical Name:
1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid
Purity:
≥98%
Potent and selective S1P1 receptor antagonist

Clone 218713 was used by HLDA to establish CD designation

Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #218713
Applications:
Flow
Detection of S1P1/EDG-1 antibody in CHO Chinese Hamster Cell Line Transfected with Human S1P1/EDG-1 and eGFP antibody by Flow Cytometry.
Reactivity:
Human
R&D Systems VersaClone cDNA Plasmids

Potent and selective S1P1 receptor antagonist; inhibits angiogenesis

Chemical Name:
3,4-Dichloro-N-[(1R)-1-[4-ethyl-5-[3-(4-methyl-1-piperazinyl)phenoxy]-4H-1,2,4-triazol-3-yl]ethyl]benzenesulfonamide
Purity:
≥98%
Potent and selective S1P1 receptor antagonist; inhibits angiogenesis

S1P1 and S1P5 agonist

Chemical Name:
4-[5-[5-Chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-1H-indole-1-butanoic acid
Purity:
≥98%
S1P1 and S1P5 agonist

S1P1 and S1P5 agonist

Chemical Name:
4-[5-[5-Chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-1H-indole-1-butanoic acid
Purity:
≥98%
S1P1 and S1P5 agonist
Results Per Page
5 10 25 50