RUNX1/CBFA2: Small Molecules and Peptides
Runt-related transcription factor 2 (RUNX1), also called CBFA2, is a DNA-binding subunit that heterodimerizes with CBF-beta to form a transcription factor that plays a role in normal hematopoiesis. Defects in CBFA2 are associated with several types of leukemia.
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RUNX1/CBFA2: Small Molecules and Peptides
Runt-related transcription factor 2 (RUNX1), also called CBFA2, is a DNA-binding subunit that heterodimerizes with CBF-beta to form a transcription factor that plays a role in normal hematopoiesis. Defects in CBFA2 are associated with several types of leukemia.
Core binding factor inhibitor; attenuates hematopoiesis
| Alternate Names: | CBFβ-Runx1 inhibitor II |
| Chemical Name: | 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one |
| Purity: | ≥98% (HPLC) |