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62 results for "RBX1" in Products

RBX1 Products

ROC1 is a component of the SCF (SKP1-CUL1-F-box protein) and the CBC(VHL) (CUL2-elonging BC-VHL) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. ROC1 appears to recruit the E2 ubiquitination enzyme through the RING-type zinc finger in a manner similar to CDC34, and brings it into close proximity to the substrate. The RING-type zinc finger domain is essential for ubiquitin ligase activity. ROC1 probably also stimulates CDC34 autoubiquitination and promotes the neddylation of CUL1 and probably CUL2. ROC1 has a cytoplasmic and nuclear localization and is widely expressed in most tissues.

Source: Sf 21 (baculovirus)
Accession #: Q13619.3 (CUL4A); P62877.1 (RBX1); Q16531.1 (DDB1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Source: Sf 21 (baculovirus)
Accession #: Q13616.2 (CUL1), P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

His10

Source: Sf 21 (baculovirus)
Accession #: Q13618.2 (CUL3); P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Source: Sf 21 (baculovirus)
Accession #: Q13619.3 (CUL4A), P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

His10 Neddylated

Source: Sf 21 (baculovirus)
Accession #: Q13619.3 (CUL4A); P62877.1 (RBX1); Q16531.1 (DDB1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

His-tag

Source: Sf 21 (baculovirus)
Accession #: Q13617.2 (CUL2), P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Source: Sf 21 (baculovirus)
Accession #: Q13616.2 (CUL1), P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Source: Sf 21 (baculovirus)
Accession #: Q13617.2 (CUL2), P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF
Western Blot: RBX1 Antibody [NBP2-20113]
(2)
Source: Sf 21 (baculovirus)
Accession #: Q13618.2 (CUL3); P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Source: Sf 21 (baculovirus)
Accession #: Q13619.3 (CUL4A), P62877.1 (RBX1)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #SR1116
Applications: IHC, WB, ICC/IF, Flow, IP
Applications: WB, ELISA, MA, AP
SDS-PAGE: Recombinant Human RBX1 GST (N-Term) Protein [H00009978-P01]
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: IHC, WB
RBX1 Antibody
(2)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 kappa Monoclonal Clone #24GB7170
Applications: WB, ICC/IF, Flow, Mycoplasma
Reactivity: Human
Details: Mouse IgG2b Monoclonal Clone #1076128
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