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2 results for "RAGE/AGER" in Products
RAGE/AGER Products
RAGE (Receptor for Advanced Glycation End product) is a transmembrane glycoprotein that binds advanced glycation end products (AGEs), beta-amyloid peptides, HMGB1/Amphoterin, and several S100 family proteins. AGEs are adducts formed by the non-enzymatic glycation and oxidation of proteins and lipids. A soluble form can also be generated by MMP-mediated shedding. RAGE is expressed in the CNS during development as well as in adult endothelial cells, smooth muscle cells, pericytes, monocytes, and ...
High affinity antagonist of RAGE
Chemical Name:
4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
Purity:
≥98%
ctRAGE-DIAPH1 interaction antagonist; reduces inflammatory signaling in diabetic mice
Chemical Name:
N-[4-[7-Cyano-4-(4-morpholinylmethyl)-2-quinolinyl]phenyl]acetamide
Purity:
≥98%
