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13 results for "PDGF Receptor Inhibitors" in Products
PDGF Receptor Inhibitors
Potent and selective PDGFR family inhibitor
Chemical Name:
N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide
Purity:
≥98%
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
Alternate Names:
Gleevec,CGP 57148B
Chemical Name:
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
Purity:
≥98%
Potent VEGFR, PDGFR and FGFR inhibitor
Chemical Name:
Methyl (Z)-3-[[[4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene]-2-oxoindoline-6-carboxylate
Purity:
≥98%
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
Chemical Name:
6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride
Purity:
≥98%
Potent and selective PDGFRβ inhibitor
Chemical Name:
5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
Purity:
≥98%
Potent and selective PDGFR inhibitor
Chemical Name:
1-[2-[5-(2-Methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine
Purity:
≥98%
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
Chemical Name:
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Purity:
≥98%
Potent VEGFR, PDGFRβ and KIT inhibitor
Alternate Names:
SU 11248
Chemical Name:
N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt
Purity:
≥98%
Potent multi-kinase and pan-Bcr-Abl inhibitor
Alternate Names:
Ponatinib
Chemical Name:
3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide
Purity:
≥98%
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
Chemical Name:
2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
Purity:
≥98%
Potent inhibitor of VEGFR, PDGFR and FGFR
Chemical Name:
4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline
Purity:
≥98%
Potent VEGFR inhibitor; also aromatase inhibitor
Alternate Names:
CGP 79787D,PTK787/ZK222584
Chemical Name:
N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate
Purity:
≥98%
Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
Chemical Name:
N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea
Purity:
≥98%
