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p27/Kip1: Proteome Profiler Antibody Arrays

The cyclin-dependent kinase (cdk) inhibitor p27/Kip1 is a tumor suppressor protein that acts in the nucleus to enforce cell cycle checkpoints. p27/Kip1 binds to and inhibits many cyclin/cdk complexes, including cyclin D/cdk4, cyclin E/cdk2, and cyclin A/cdk2. This inhibition can subsequently block progression through different phases of the cell cycle. p27/Kip1 is phosphorylated at T198 in cells treated with the AMP-dependent protein kinase (AMPK) activator AICAR (5-amino-4-imidazolecarboxamide riboside) or glucose withdrawal.

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5 results for "p27/Kip1 Proteome Profiler Antibody Arrays" in Products

5 results for "p27/Kip1 Proteome Profiler Antibody Arrays" in Products

p27/Kip1: Proteome Profiler Antibody Arrays

The cyclin-dependent kinase (cdk) inhibitor p27/Kip1 is a tumor suppressor protein that acts in the nucleus to enforce cell cycle checkpoints. p27/Kip1 binds to and inhibits many cyclin/cdk complexes, including cyclin D/cdk4, cyclin E/cdk2, and cyclin A/cdk2. This inhibition can subsequently block progression through different phases of the cell cycle. p27/Kip1 is phosphorylated at T198 in cells treated with the AMP-dependent protein kinase (AMPK) activator AICAR (5-amino-4-imidazolecarboxamide riboside) or glucose withdrawal.

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Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins

Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies

Contains 4 membranes - each spotted in duplicate with 26 different cell stress antibodies

Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies

Contains 8 membranes - each spotted in duplicate with 21 different apoptosis antibodies

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