5 results for "NPY2R Small Molecules and Peptides" in Products
NPY2R: Small Molecules and Peptides
NPY2R is widely expressed in the central nervous system, with particularly high abundance in the hypothalamus. The hypothalamus is known to be important for appetite regulation and thus variants in this gene could be associated with obesity.
Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
| Alternate Names: | BIIE 0246 2HCl,BIIE0246 2HCl |
| Chemical Name: | N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]-cyclopentaneacetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective NPY Y2 receptor agonist
| Alternate Names: | PYY 3-36 |
| Purity: | ≥95% (HPLC) |
Potent and selective D1-like agonist; orally active
| Chemical Name: | (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride |
| Purity: | ≥98% (HPLC) |
NPY Y2 receptor antagonist
| Chemical Name: | N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide |
| Purity: | ≥98% (HPLC) |
Potent NPY Y2 receptor antagonist
| Chemical Name: | N-[4-[(Dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide |
| Purity: | ≥98% (HPLC) |
