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5 results for "notch-signaling-inhibitors&view=expanded" in Products

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name:
(2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity:
≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)

pan-Notch inhibitor; also inhibits differentiation of mural cells by downregulating Notch pathway.

Alternate Names:
Limantrafin
Chemical Name:
6-[4-(1,1-Dimethylethyl)phenoxy]-3-pyridinamine
Purity:
≥98%
pan-Notch inhibitor; also inhibits differentiation of mural cells by downregulating Notch pathway.

γ-secretase inhibitor; inhibits Notch pathway

Alternate Names:
Dibenzazepine,YO-01027
Chemical Name:
N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity:
≥98%
γ-secretase inhibitor; inhibits Notch pathway

Potent and selective γ-secretase inhibitor; also induces differentiation of iEM cells into luminal cells

Alternate Names:
RG-4733
Chemical Name:
2,2-Dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide
Purity:
≥98%
Potent and selective γ-secretase inhibitor; also induces differentiation of iEM cells into luminal cells

Inhibitor of SLC39A7 (ZIP7) zinc transporter; induces apoptosis and inhibits ferroptosis.

Chemical Name:
1-[(2S)-2-[(6-Fluoro-2-benzothiazolyl)amino]-3-phenylpropyl]-spiro[piperidine-4,4'(1'H)-quinazolin]-2'(3'H)-one
Purity:
≥98%
Inhibitor of SLC39A7 (ZIP7) zinc transporter; induces apoptosis and inhibits ferroptosis.
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