MGMT: Small Molecules and Peptides
The O-6-methylguanine-DNA-methyl transferase (MGMT) is involved in the direct repair of DNA alkylated at the O6 position of guanine. MGMT transfers the alkyl group to its own cysteine thereby inactivating the MGMT molecule. Therefore, the number of MGMT molecules correlates directly with the cell's ability to withstand DNA alkylation.
3 results for "MGMT Small Molecules and Peptides" in Products
3 results for "MGMT Small Molecules and Peptides" in Products
MGMT: Small Molecules and Peptides
The O-6-methylguanine-DNA-methyl transferase (MGMT) is involved in the direct repair of DNA alkylated at the O6 position of guanine. MGMT transfers the alkyl group to its own cysteine thereby inactivating the MGMT molecule. Therefore, the number of MGMT molecules correlates directly with the cell's ability to withstand DNA alkylation.
DNA methyltransferase inhibitor
| Alternate Names: | 2'-Deoxy-5-azacytidine,5-Aza-2'-deoxycytidine,NSC 127716 |
| Chemical Name: | 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one |
| Purity: | ≥98% (HPLC) |
DNA methyltransferase inhibitor
| Chemical Name: | 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one |
| Purity: | ≥98% (HPLC) |
Non-nucleoside DNA methyltransferase inhibitor
| Chemical Name: | N-Phthalyl-L-tryptophan |
| Purity: | ≥98% (HPLC) |
