INSIG-1 Products
Insig1 is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells.
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
35 results for "INSIG-1" in Products
35 results for "INSIG-1" in Products
INSIG-1 Products
Insig1 is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells.
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Show More
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: INSIG-1 AntibodyBSA Free [NB110-55244]](https://resources.bio-techne.com/images/products/INSIG-1-Antibody-Western-Blot-NB110-55244-img0002.jpg "Western Blot: INSIG-1 AntibodyBSA Free [NB110-55244]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: INSIG-1 Antibody [NBP2-84095]](https://resources.bio-techne.com/images/products/INSIG-1-Antibody-Western-Blot-NBP2-84095-img0001.jpg "Western Blot: INSIG-1 Antibody [NBP2-84095]")
| Applications: | WB |
![Western Blot: INSIG-1 Overexpression Lysate [NBP2-04727]](https://resources.bio-techne.com/images/products/INSIG-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-04727-img0001.jpg "Western Blot: INSIG-1 Overexpression Lysate [NBP2-04727]")
| Applications: | WB |
![Western Blot: INSIG-1 Overexpression Lysate [NBL1-12003]](https://resources.bio-techne.com/images/products/INSIG-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12003-img0002.jpg "Western Blot: INSIG-1 Overexpression Lysate [NBL1-12003]")
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Applications: WB, ICC/IF
Reactivity:
Human,
Rat
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |