INSIG-1 Antibody - BSA Free

Western Blot: INSIG-1 AntibodyBSA Free [NB110-55244]

Western Blot: INSIG-1 Antibody [NB110-55244] - Detection of Insig 1 in HepG2 lyaste using NB110-55244.

Immunocytochemistry/ Immunofluorescence: INSIG-1 Antibody - BSA Free [NB110-55244]

Immunocytochemistry/Immunofluorescence: INSIG-1 Antibody [NB110-55244] - INSIG-1 antibody was tested in HepG2 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Western Blot: INSIG-1 Antibody - BSA Free [NB110-55244] -

Validation of interaction between TDP-43 and SREBP2. (A) Post-translational modification of SREBP2. Anchor protein SCAP induces SREBP2 to translocate from endoplasmic reticulum (ER) to Golgi apparatus. SREBP2 is cleaved by S1P/S2P protease, and N-terminal SREBP2 is translocated to bind the SRE transcriptional domain of DNA for expression of target genes. (B) Immunoblots of proteins controlling SREBP processing pathway in TDP-43 abundant condition (Dox+) in comparison with cholesterol depleted condition. S: cholesterol-sufficient condition, D: cholesterol-depleted condition. The panels were cropped from original blots presented in Supplementary Fig. 3. (C) Quantification of the protein levels of cholesterol-related factors relative to beta-actin between Dox− and Dox+ condition; *p < 0.05, t-test, error bars = s.d. n = 3. (D) HEK293T cells were transfected with or without pcDNA3.1-TDP-43 and pFLAG-NSREBP2 (1–481) and the lysates were immunoprecipitated with FLAG antibody for the following immunoblots using TDP-43 antibody. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/35568729), licensed under a CC-BY license. Not internally tested by Novus Biologicals.