IL-8/CXCL8: Proteome Profiler Antibody Arrays
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
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7 results for "IL-8/CXCL8 Proteome Profiler Antibody Arrays" in Products
7 results for "IL-8/CXCL8 Proteome Profiler Antibody Arrays" in Products
IL-8/CXCL8: Proteome Profiler Antibody Arrays
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
Products:
Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
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Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
Contains 4 membranes - each spotted in duplicate with 31 different chemokine antibodies
Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies