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8 results for "Glucagon-Like Peptide 1 Receptor Agonists" in Products

Glucagon-Like Peptide 1 Receptor Agonists Products

Glucagon-like peptide 1 (GLP-1) receptors are members of the glucagon receptor family that also includes glucagon, GLP-2, secretin, GHRH and GIP receptors. GLP-1 receptors are found both centrally (hypothalamus and brainstem) and peripherally (pancreatic islet cells, stomach and heart).

GLP-1 receptors mediate the effects of the incretin axis; the functional connection between the intestine and the islets of Langerhans in the pancreas. Activation stimulates insulin release from the islet β-cells in a glucose-dependent manner and suppresses glucagon secretion from islet α-cells. In addition, GLP-1 receptors delay gastric emptying and regulate appetite. The human GLP-1 receptor gene is localized on chromosome 6p21.

Potent insulinotropic peptide

Endogenous pancreatic peptide

Endogenous bioactive GLP-1 receptor ligand

Highly potent, long-acting GLP-1 receptor agonist

Potent GLP-1 receptor agonist

Highly potent, long-acting GLP-1 receptor agonist

Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator

GSDMD (Gasdermin D) agonist, activator of pyroptosis, also GLP-1R agonist

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