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315 results for "GLI-1" in Products

GLI-1 Products

GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI-1 is a member of the Krupple family of zinc finger proteins. GLI-1 is activated by the sonic hedgehog pathway and influences transcription of a variety of target genes by binding to the consensus site 5CGGGTGGTC3. GLI- activation leads to cellular proliferation and anti-apoptotic activities based on target genes activated.

Reactivity: Human, Mouse, Canine, Porcine
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ELISA, ICC/IF, Flow, +2 More
Knockdown Validated: GLI-1 Antibody - BSA Free [NB600-600]
(6)

GLI antagonist; inhibits Hedgehog (Hh) signaling

Chemical Name: 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
Purity: ≥98% (HPLC)
GLI antagonist; inhibits Hedgehog (Hh) signaling
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, Func, Endotoxin
Immunohistochemistry: GLI-1 Antibody - BSA Free [NBP1-78259]
(6)
Reactivity: Human, Mouse
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse
Details: Goat IgG Polyclonal
Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #OTI4E2
Applications: IHC, WB, Mycoplasma
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, Func
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