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399 results for "Flt-3/Flk-2" in Products

Flt-3/Flk-2 Products

The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.

Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)

VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Alternate Names: Semaxinib
Chemical Name: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Purity: ≥98% (HPLC)
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies

The Mouse Phospho-RTK Array detects multiple tyrosine phosphorylated receptors in untreated and ligand-treated cell lysates.

Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT

Chemical Name: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Purity: ≥98% (HPLC)
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #66903
Applications: Flow, CyTOF-ready
(2)
Source: NS0
Accession #: AAA18947
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #66903
Applications: Flow
Detection of Flt-3/Flk-2 antibody in THP-1 Human Cell Line antibody by Flow Cytometry.
Reactivity: Mouse
Details: Rat IgG2a Monoclonal Clone #113308
Applications: Flow, CyTOF-ready, ICC
(2)

Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R

Chemical Name: N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea
Purity: ≥98% (HPLC)
Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R

JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Alternate Names: CEP-701
Chemical Name: (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
Purity: ≥98% (HPLC)
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, Simple Western, ICC
Detection of Human Phospho-Flt-3/Flk-2 (Y591) antibody by Western Blot.
(3)
Source: HEK293
Accession #: P36888
Applications: BA
Recombinant Human Flt-3/Flk-2 His-tag Protein Binding Activity
(2)
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #66903
Applications: Flow
Detection of Flt-3/Flk-2 antibody in THP-1 Human Cell Line antibody by Flow Cytometry.
Reactivity: Human
Details: Mouse IgG2b Lambda Monoclonal Clone #7E8.2C8
Applications: IHC, WB, ICC/IF, Flow, CyTOF-ready
Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)Azide and BSA Free [NBP2-80739]
(3)

Potent FLT3 inhibitor

Chemical Name: 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide
Purity: ≥98% (HPLC)
Potent FLT3 inhibitor

PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

Chemical Name: 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
Purity: ≥98% (HPLC)
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
Source: NS0
Accession #: Q00342
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Mouse IgG2b Lambda Monoclonal Clone #7E8.2C8
Applications: IHC, WB, Flow
Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)BSA Free [NBP2-42210]
(3)

Potent FLT3 inhibitor; also potently inhibits AXL

Chemical Name: 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide
Purity: ≥98% (HPLC)
Potent FLT3 inhibitor; also potently inhibits AXL
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