DC-STAMP: cDNA Clones

Dendritic cells are unique in their ability to present antigen to naive T cells, and therefore play a central role inthe initiation of immune responses. The protein encoded by this gene is a transmembrane molecule that ispreferentially expressed by dendritic cells. Its expression is down-regulated by ligation of the CD40 molecule.Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of someof these variants has not been determined. (provided by RefSeq)