CRTH-2: Small Molecules and Peptides
CRTH-2 is a 7-transmembrane G-protein coupled receptor that is expressed by activated Th2 cells and eosinophils. CRTH-2 binds prostaglandin D2 and induces chemotaxis of Th2 cells and eosinophils in allergic and inflammatory immune responses. Human and mouse CRTH-2 share 78% amino acid sequence identity.
1 result for "CRTH-2 Small Molecules and Peptides" in Products
1 result for "CRTH-2 Small Molecules and Peptides" in Products
CRTH-2: Small Molecules and Peptides
CRTH-2 is a 7-transmembrane G-protein coupled receptor that is expressed by activated Th2 cells and eosinophils. CRTH-2 binds prostaglandin D2 and induces chemotaxis of Th2 cells and eosinophils in allergic and inflammatory immune responses. Human and mouse CRTH-2 share 78% amino acid sequence identity.
Dual TP/DP2 (CRTH2) receptor antagonist
| Alternate Names: | Ramatroban |
| Chemical Name: | (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid |
| Purity: | ≥98% (HPLC) |
