12 results for "CaM Kinase Inhibitors" in Products
CaM Kinase Inhibitors Products
Calmodulin-dependent kinases (CaMK) are a family of serine/threonine kinases that mediate many of the second messenger effects of Ca2+. At basal Ca2+ levels, CaMKs are maintained in a dormant state through autoinhibition. Increases in Ca2+ levels allows calmodulin to relieve this autoinhibition and activate the kinase activity.
There are two main classes of CaMKs; mulitfunctional CaMKs (CaMKK, CaMKI, CaMKII and CaMKIV) which have multiple downstream targets and substrate-specific CaMKs (CaMKIII) ...
Selective CaM kinase kinase inhibitor
| Chemical Name: | 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate |
| Purity: | ≥98% (HPLC) |
CaM kinase III (eEF-2 kinase) inhibitor
| Chemical Name: | 1-Hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium iodide |
CaM kinase II inhibitor; water soluble version of KN 93 (Cat. No. 1278)
| Chemical Name: | N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate |
| Purity: | ≥98% (HPLC) |
CaM kinase II inhibitor; also K+ channel blocker (KV)
| Chemical Name: | N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide |
| Purity: | ≥98% (HPLC) |
Selective CaM kinase II inhibitor
| Alternate Names: | AIP |
| Purity: | ≥95% (HPLC) |
Potent CaM kinase I inhibitor
| Chemical Name: | 2-[(3S)-3-Amino-1-piperidinyl]-4-[[2,6-bis(1-methylethyl)-4-pyridinyl]amino]-5-pyrimidinecarboxamide |
| Purity: | ≥98% (HPLC) |
CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide
| Alternate Names: | Myr-AIP,AIP Myristoylated |
| Purity: | ≥95% (HPLC) |
Non-competitive P2X7 antagonist
| Chemical Name: | 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester |
| Purity: | ≥98% (HPLC) |
Potent and selective calcium/calmodulin-dependent serine protein kinase (CASK) inhibitor
| Chemical Name: | 4-(Cyclopentylamino)-2-((2,5-dibromo-4-methylbenzyl)amino)-N-(3-(2-oxooxazolidin-3-yl)propyl)pyrimidine-5-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective CAMKK1/2 inhibitor
| Chemical Name: | 2-Cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid |
| Purity: | ≥95% (HPLC) |
Staurosporine synthesized to Ancillary Material Grade
| Chemical Name: | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one |
| Purity: | ≥98% |
CaM kinase III (eEF-2 kinase) inhibitor
| Chemical Name: | 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide |
| Purity: | ≥98% (HPLC) |
