Cadherin-13: Proteins and Enzymes

Cadherin-13, also known as T-Cadherin and H‑Cadherin, is a GPI-anchored protein belonging to the Cadherin superfamily of calcium-dependent adhesion molecules. Cadherin-13 is most highly expressed in the circulatory and nervous systems, particularly on cardiac myocytes, vascular endothelial and smooth muscle cells, and neurons and astrocytes in the brain. It exerts a negative influence on neurite extension, and it is downregulated in neurons upon NGF stimulation. Homotypic Cadherin-13 ...